Program Schedule
Updated as of 4 Jan 2016
Dates: 4 - 8 January, 2016
4 Jan | 5 Jan | 6 Jan | 7 Jan | 8 Jan
4 Jan 2016 (Mon)
|
Time |
Event |
|
Session 1: Structural Basis of Transcription
[chair: Robert Landick] |
|
08:30-09:00 |
Registration (* Shuttle bus pick-up from Holiday Inn Express at 08:30) |
|
09:00-09:20 |
Opening Remarks |
|
09:20-10:00 |
“Structural Basis of RNA Polymerase II Initiation”
Patrick Cramer (The Max Planck Institute for Biophysical Chemistry)
|
|
10:00-10:40 |
“Using the Time-Resolved X-Ray Crystallography to Monitor Nucleic
Acid Polymerases Choose Right from Wrong”
Katsuhiko Murakami (Pennsylvania State University)
|
| 10:40-11:10 |
Coffee break |
|
11:10-11:50 |
“Structural Studies on RNA Polymerase I”
Carlos Fernández Tornero (The Spanish National Research Council (CSIC))
|
|
11:50-12:30 |
“Structure of an RNA Polymerase II Preinitiation Complex”
Kenji Murakami (University of Pennsylvania)
|
| 12:30-14:00 |
Lunch (for registered participants only) |
|
Session 2: Mechanism and Modeling
[chair: Dong Wang] |
|
14:00-14:40 |
“Simulations of Pol II Transcription Elongation Mechanisms”
Xuhui Huang (The Hong Kong University of Science and Technology)
|
|
14:40-15:20 |
“Investigation of Transcription Elongation Factors in
RNA Polymerase Dynamics”
Toyotaka Ishibashi (The Hong Kong University of Science and Technology) |
|
15:20-16:00 |
“NTP Entry and Fidelity in RNA Polymerase II from Computer
Simulations”
Michael Feig (Michigan State University) |
| 16:00-16:30 |
Coffee break |
|
16:30-17:10 |
“Mapping the Distinct Configurations of Nucleic Acids
in Transcription Complexes by Kinetic and Biophysical
Methods”
Georgi Belogurov (University of Turku) |
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5 Jan 2016 (Tue)
|
Time |
Event |
|
Session 3: Initiation/ Mechanisms
[chair: Xuhui Huang] |
|
09:00-09:40 |
“Structural Studies of Bacterial Transcription”
Seth Darst (The Rockefeller University) |
|
09:40-10:20 |
“Mediator-Dependent Activation of the PIC”
Sohail Malik (The Rockefeller University) |
| 10:20-10:50 |
Coffee break |
|
10:50-11:30 |
“The Mechanism of Initial DNA Unwinding in Eukaryotic Transcription”
Eric Galburt (Washington University in St. Louis) |
|
11:30-12:10 |
“Structural and Biochemical Studies of Mycobacterial Specific
Transcription Factors”
Elizabeth Campbell (The Rockefeller University) |
| 12:10-14:00 |
Lunch (for registered participants only) |
|
14:00-18:30 |
Free time (boat trip for invited participants) |
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6 Jan 2016 (Wed)
|
Time |
Event |
|
Session 4: Elongation/ Regulation
[chair: Joan Conaway] |
|
09:00-09:40 |
“Genome-wide Views of the Mechanisms of Transcriptional Regulation”
John Lis (Cornell University) |
|
09:40-10:20 |
“Gene Expression Control by RfaH”
Irina Artsimovitch (The Ohio State University) |
| 10:20-10:50 |
Coffee break |
|
10:50-11:30 |
“Overcoming Barriers to RNAPII Transcription”
Joseph Reese (Pennsylvania State University) |
|
11:30-12:10 |
“Modeling Fluctuation and Control in Transcription
Elongation from T7 RNA Polymerase to Polymerase II”
Jin Yu (Beijing Computational Science Research Center) |
| 12:10-14:00 |
Lunch (for registered participants only) |
|
Session 5: Coupling of Transcription
Elongation and DNA Damage Processing
[chair: David Price] |
|
14:00-14:40 |
“Mechanism of Polymerase II Transcription Elongation and DNA
Modification Recognition”
Dong Wang (University of Wisconsin-Madison) |
|
14:40-15:20 |
“Elongin and the Elongin A Ubiquitin Ligase Complex in Transcription
and the Response to DNA Damage”
Joan Conaway (Stowers Institute for Medical Research) |
| 15:20-15:50 |
Coffee break |
|
15:50-16:30 |
“The Transcription-Related DNA Damage Response”
Jesper Svejstrup (The Francis Crick Institute) |
|
16:30-17:10 |
“New Principles of Transcription-Coupled DNA Repair”
Evgeny Nudler (New York University) |
|
17:10-17:50 |
“Signatures of Replication-Transcription Conflicts in Bacteria”
Jade Wang (University of Wisconsin-Madison) |
| 18:00-20:30 |
Dinner banquet (by
invitation only) |
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7 Jan 2016 (Thu)
|
Time |
Event |
|
Session 6: Genome-scale Transcription
[chair: Jesper Svejstrup] |
|
09:00-09:40 |
“Transcription in the Archaea - From Molecules to Systems”
Finn Werner (University College London) |
|
09:40-10:20 |
“Roles of Cohesin in Regulating Genome Structure and Function during
Active Transcription”
Xin Liu (University of Texas Southwestern Medical Center) |
| 10:20-10:50 |
Coffee break |
|
10:50-11:30 |
“Molecular Features of Chromatin Modifiers that Travel with
Elongating RNA Polymerase II”
Bing Li (University of Texas Southwestern Medical Center) |
|
11:30-12:10 |
“Nuclear Walk - On the Wild Side”
David Price (University of Iowa) |
| 12:10-14:00 |
Lunch (for registered participants only) |
|
Session 7: Mechanisms of Transcription II
[chair: Irina Artsimovitch] |
|
14:00-14:40 |
“Mechanism and Regulation of Transcriptional Pausing”
Robert Landick (University of Wisconsin-Madison) |
|
14:40-15:20 |
“Experimental and Theoretical Approaches to Study Molecular Machines
Involved in Transcription”
Robert Weinzierl (Imperial College London) |
| 15:20-15:50 |
Coffee break |
|
15:50-16:30 |
“Mechanisms of Catalysis and Regulation in Viral RNA-Dependent RNA
Polymerases”
Peng Gong (Wuhan Institute of Virology, Chinese Academy of Sciences) |
|
16:30-17:10 |
“Fundamental Understandings from a Model RNA Polymerase”
Craig Martin (University of Massachusetts Amherst) |
|
17:10-17:20 |
Jianfei Zhao (Nature Communications) |
|
17:20-17:35 |
Closing Remarks |
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8 Jan 2016 (Fri)
|
Time |
Event |
|
|
IAS Distinguished Lectures (Location: IAS Lecture Theater, G/F) |
|
14:30-16:00 |
“Structural Biology of Bacterial Transcription: Electron Microscopy to X-ray Crystallography and Back Again”
[Details]
Seth Darst (The Rockefeller University) |
|
16:00-17:30 |
“Genome-wide Views of the Mechanisms of Transcriptional Regulation”
[Details]
John Lis (Cornell University) |
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Venue
IAS 4042, 4/F, Lo Ka Chung Building, Lee Shau Kee Campus, The Hong Kong University of Science & Technology
|
