Program Schedule (December 7-11, 2020)
(Updated as of December 8, 2020)
Important notes:
| 1. | The video should be viewed ONLINE ONLY, download/recording of the video are prohibited. |
| 2. | You are suggested to watch the video before joining the Zoom meeting. |
| 3. | The online Zoom discussion sessions will be organized during Dec 7-11, 22:30 - 24:30 (HKT, GMT+8). The Zoom ID with password will be sent by email. |
| 4. | You can leave your comments/questions in the Comments section of the video pages before the online discussion sessions begin. |
| Should you have further enquiries, please feel free to contact the program secretariat by email at iasmtir2020@ust.hk. | |
Day 1
December 7, 2020 (Monday)
Time
Event
| Opening Remarks | ||
| Chairs: Xuhui HUANG & Toyotaka ISHIBASHI (HKUST) | ||
| Online via Zoom - 22:30 - 24:30 HKT (GMT+8) | ||
| M0-01 | Nancy IP (Vice-President for Research and Development, and The Morningside Professor of Life Science, HKUST) | |
| M0-02 | Andrew G. COHEN (Director of HKUST Jockey Club Institute for Advanced Study, Acting Dean of Science, and Lam Woo Foundation Professor, HKUST) | |
| Session 1 | ||
|
Structure and Dynamics of Transcriptional Machinery Chairs: Robert LANDICK (University of Wisconsin-Madison) & Terence STRICK (École Normale Supérieure, Paris) |
||
| Online discussion via Zoom - 22:30 - 24:30 HKT (GMT+8) | ||
| M1-01 |
"Structural Biology of RNA Polymerase I and III Transcription" [Presentation Video] Christoph MÜLLER (European Molecular Biology Laboratory) |
|
| M1-02 |
"Structural Basis of Ribosomal RNA Transcription Regulation" [Presentation Video] Katsuhiko MURAKAMI (The Pennsylvania State University) |
|
| M1-03 |
"Transcription Factors and Antibiotics That Affect Promoter Melting Steps in Mycobacterium Tuberculosis" [Presentation Video] Elizabeth CAMPBELL (The Rockefeller University) |
|
| M1-04 |
"Role of Bacterial RNA Polymerase Gate Opening Dynamics in DNA Loading and Antibiotics" [Presentation Video] Xuhui HUANG (HKUST) |
|
| M1-05 |
"A Structure of Plant Pol IV, a Pol II-derived Multiple-subunit RNA Polymerase in Plant" [Presentation Video] Yu ZHANG (Chinese Academy of Sciences) |
|
Day 2
December 8, 2020 (Tuesday)
Time
Event
| Session 2 | ||
|
Interfaces between Transcription and DNA Repair Chairs: Jesper SVEJSTRUP (University of Copenhagen) & Dong WANG (University of California, San Diego) |
||
| Online discussion via Zoom - 22:30 - 24:50 HKT (GMT+8) | ||
| Tu1-01 |
"Transcription-coupled Lesion Recognition" [Presentation Video] Dong WANG (University of California, San Diego) |
|
| Tu1-02 |
"Transcription-coupled Repair: from DNA Repair to Evolution and Back Again" [Presentation Video] Terence STRICK (École Normale Supérieure, Paris) |
|
| Tu1-03 |
"Transcription-coupled DNA Damage Recognition and Repair" [Presentation Video] Carlos FERNÁNDEZ-TORNERO (Centro de Investigaciones Biológicas, Spain) |
|
| Tu1-04 |
"Structural Study on Transcription Complex Disruption by The Mfd Translocase" [Presentation Video] Jin Young KANG (Korea Advanced Institute of Science and Technology (KAIST)) |
|
| Session 3 | ||
|
Transcription-coupled Processes Chairs: Irina ARTSIMOVITCH (The Ohio State University) & Jean-Marc EGLY (French Academy of Sciences) |
||
| Online discussion via Zoom - 22:30 - 24:50 HKT (GMT+8) | ||
| Tu2-01 |
"Recent Insights into Chromatin Transcription by RNA Polymerase II" [Presentation Video] Patrick CRAMER (Max Planck Institute for Biophysical Chemistry) |
|
| Tu2-02 |
"Structural Basis of Nucleosome Transcription by RNA Polymerase II" [Presentation Video] Shun-ichi SEKINE (RIKEN) |
|
| Tu2-03 |
"Transcription during Heatshock" [Presentation Video] Jesper SVEJSTRUP (University of Copenhagen) |
|
Day 3
December 9, 2020 (Wednesday)
Time
Event
| Session 4 | ||
|
Mechanism and Regulation of Transcription Chairs: Xuhui HUANG (HKUST) & Katsuhiko MURAKAMI (The Pennsylvania State University) |
||
| Online discussion via Zoom - 22:30 - 24:30 HKT (GMT+8) | ||
| W1-01 |
"How SI3 Helps RNAP Read Pause Signals" [Presentation Video] Robert LANDICK (University of Wisconsin-Madison) |
|
| W1-02 |
"Structural Basis of Transcription-translation Coupling and Collision in Bacteria" [Presentation Video] Albert WEIXLBAUMER (Institute of Genetics and Molecular and Cellular Biology (IGBMC)) |
|
| W1-03 |
"Deep Cleaning of RNA Polymerase Prior to Storage" [Presentation Video] Irina ARTSIMOVITCH (The Ohio State University) |
|
| W1-04 |
"The Mechanism of The Nucleo-sugar Selection by Multi-subunit RNA Polymerases" [Presentation Video] Georgi BELOGUROV (University of Turku) |
|
| W1-05 |
"pH-responsive Riboswitch in E. Coli: Kinetic Control and Folding Outcomes" [Presentation Video] Tatiana MISHANINA (University of California, San Diego) |
|
| W1-06 |
"Dissecting Nucleotide Selectivity of a Viral RNA Polymerase: A Kinetics Framework and Atomic Simulations" [Presentation Video] Jin YU (University of California, Irvine) |
|
Day 4
December 10, 2020 (Thursday)
Time
Event
| Session 5 | ||
|
Transcription Dynamics and Epigenetic Regulation Chairs: John LIS (Cornell University; HKUST IAS Senior Visiting Fellow) & Bing REN (University of California, San Diego) |
||
| Online discussion via Zoom - 22:30 - 24:30 HKT (GMT+8) | ||
| Th1-01 |
"Pioneer Factor GAF Cooperates with PBAP (SWI/SNF) and NURF (ISWI) Remodelers to Regulate Transcription" [Presentation Video] John LIS (Cornell University; HKUST IAS Senior Visiting Fellow) |
|
| Th1-02 |
"Genome-wide Mapping of Protein-DNA Interaction Dynamics" [Presentation Video] Steven HENIKOFF (Fred Hutchinson Cancer Research Center) |
|
| Th1-03 |
"CTCF Mediates Dosage and Sequence-context-dependent Transcriptional Insulation" [Presentation Video] Bing REN (University of California, San Diego) |
|
| Th1-04 |
"Yeast BET Family Bromodomain Factors Bdf1/2 Link Genome-wide Transcription and Histone Acetylation" [Presentation Video] Steven H. HAHN (Fred Hutchinson Cancer Research Center) |
|
| Session 6 | ||
|
Single-molecular Transcription Dynamics Chairs: Toyotaka ISHIBASHI (HKUST) & Michelle D. WANG (Cornell University) |
||
| Online discussion via Zoom - 22:30 - 24:30 HKT (GMT+8) | ||
| Th2-01 |
"Single-molecule Dynamics of Activated RNA Polymerase II Transcription" [Presentation Video] Jeff GELLES (Brandeis University) |
|
| Th2-02 |
"Untangling DNA: Fundamental Processes under Torsion" [Presentation Video] Michelle D. WANG (Cornell University) |
|
| Th2-03 |
"Testis-specific Histone Variant H2BFW and Its Effect of Transcription Regulation in Spermatogenesis" [Presentation Video] Toyotaka ISHIBASHI (HKUST) |
|
Day 5
December 11, 2020 (Friday)
Time
Event
| Session 7 | ||
|
COVID-19 Chairs: Elizabeth CAMPBELL (The Rockefeller University) & Patrick CRAMER (Max Planck Institute for Biophysical Chemistry) |
||
| Online discussion via Zoom - 22:30 - 24:30 HKT (GMT+8) | ||
| Fr1-01 |
"Structural Basis for Inhibition of Coronavirus Replication by Remdesivir" [Presentation Video] Goran KOKIC (Max Planck Institute for Biophysical Chemistry) |
|
| Fr1-02 |
"Insights into SARS-CoV-2 Polymerase Catalysis and Remdesivir Intervention" [Presentation Video] Peng GONG (Chinese Academy of Sciences) |
|
| Fr1-03 |
"Helicase Coupling to The RdRp in COVID" [Presentation Video] Seth A. DARST (The Rockefeller University) |
|
| Fr1-04 |
"Orthogonal Use of PRO-seq in eRNA Variation and Non-canonical Transcription" [Presentation Video] Hojoong KWAK (Cornell University) |
|
| Session 8 | ||
| Happy Hour Session (By invitation only) |