Venue: Kaisa Group Lecture Theater (IAS LT), G/F, Lo Ka Chung Building, Lee Shau Kee Campus, HKUST

08:20 - 08:50	Registration
08:50 - 09:00	Opening Remarks Guojun BU (HKUST)
Session I: Lipid and Lipoprotein Trafficking in Metabolic Regulation and Disease Session Chair: Binbin DING, Guangzhou National Laboratory; Co-Chair: Xiao WANG, Peking University
09:00 - 09:45	Keynote Lecture: Lipid Control of Membrane Dynamics in Health and Disease: From Membrane Repair to Synapse Function Volker HAUCKE (Free University of Berlin)
09:45 - 10:10	The Phase of Fat: Mechanisms of Membrane Trafficking to Lipid Droplets Tobias WALTHER (Memorial Sloan Kettering Cancer Center)
10:10 - 10:35	Peroxisome-derived Ether Lipids Regulate Lysosomal Function Ming LI (University of Michigan)
10:35 - 10:50	Structural & Functional Studies of HsPQLC1: A PQ-Loop Scramblase Involved in Endosome Biogenesis Jieqiong GAO (HKUST)
10:50 - 11:10	Group Photo and Coffee Break
11:10 - 11:35	ApoE in Lipid Transport and Alzheimer’s Disease Guojun BU (HKUST)
11:35 - 12:00	How (We Think) Bridge-like Proteins in the VPS13 Family Transfer Bulk Lipid Karin REINISCH (Yale University)
12:00 - 12:25	A Conserved ER Protein Prevents Lipotoxicity by Stimulating Glycerol-3-Phosphate Acyltransferase GPAT4 in Glycerolipid Synthesis Ho Yi MAK (HKUST)
12:25 - 14:00	Lunch Break and Poster Session
Session II: Autophagy and Organelle Biogenesis and Function Session Chair: Pengli ZHENG, Peking University; Co-Chair: Fang XU, Guangzhou Medical University
14:00 - 14:45	Keynote Lecture: Dynamic Ca2+ Signals Drive Autophagosome Formation Hong ZHANG (Institute of Biophysics, Chinese Academy of Sciences)
14:45 - 15:10	A Conserved Herpesvirus Tegument Protein ORF42 is Involved in Secondary Envelopment of Viral Particles Hongyu DENG (Institute of Biophysics, Chinese Academy of Sciences)
15:10 - 15:35	Structure and Function of the Tubular ER Junjie HU (Institute of Biophysics, Chinese Academy of Sciences)
15:35 - 15:50	Neural-Specific Autophagy Regulation Yan ZHAO (Southern University of Science and Technology)
15:50 - 16:10	Coffee Break
16:10 - 16:35	Talk title to be confirmed Li YU (Tsinghua University)
16:35 - 17:00	Mitochondrial Contribution to Peroxisome Proteome Min ZHUANG (ShanghaiTech University)
17:00 - 17:25	Non-canonical Autophagosome: An Emerging Regulatory Hub for the cGAS-STING Pathway Yueguang RONG (University of Macau)
17:25 - 17:50	Multifaceted Roles of the ATG8 Protein Family in Plant Autophagy Xiaohong ZHUANG (The Chinese University of Hong Kong)
17:50 - 18:30	Flash Talks and Poster Session
18:30 - 20:30	Dinner (By invitation; Location: UniQue, HKUST Conference Lodge)

 

Session III: Endocytosis and Lysosomal Functions Session Chair: Tao NI, The University of Hong Kong; Co-Chair: Nan LIU, The University of Hong Kong
09:00 - 09:45	Keynote Lecture: Molecular Insights into Lysosomal Biogenesis and Stress Response Christian UNGERMANN (Osnabrück University)
09:45 - 10:10	The Lysosome in Nutrient Sensing and Cellular Growth Control Roberto ZONCU (University of California, Berkeley)
10:10 - 10:35	Lysosome Homeostasis in Neurodegenerative Diseases Yihong YE (Chinese Institute for Brain Research, Beijing)
10:35 - 10:50	Regulation of Lysosomal Homeostasis in the Endocytic Pathway Huaqing CAI (Institute of Biophysics, Chinese Academy of Sciences)
10:50 - 11:05	Coffee Break
11:05 - 11:30	Stress, Rupture and Repair: Cellular Responses to Lysosomal Damage Phyllis HANSON (University of Michigan)
11:30 - 11:55	Molecular Physiology of Lysosomes Haoxing XU (Zhejiang University)
11:55 - 12:20	Lysosomal Homeostasis: Regulation and Function Xiaochen WANG (Southern University of Science and Technology)
12:20 - 14:00	Lunch Break and Poster Session
Session IV: Therapeutics and New Perspectives of Membrane Trafficking Session Chair: Ruoxi WANG, Southern University of Science and Technology; Co-Chair: Xiao TANG, Anhui Normal University
14:00 - 14:45	Keynote Lecture: Linking the ER Stress-sensing Machinery to Peroxisomal Lipid Import Peter WALTER (University of California, San Francisco)
14:45 - 15:10	Comparison of Two Pathways of Interleukin-1β Secretion in Physiological Settings Liang GE (Tsinghua University)
15:10 - 15:35	XunZi, an AI Biologist, Reveals Novel Disease-modifying Targets Da JIA (Sichuan University)
15:35 - 15:50	Relocation of Sphingolipid Metabolism by Zika Virus Triggers Inflammatory Responses and Microcephaly Min ZHANG (Tsinghua University)
15:50 - 16:10	Coffee Break
16:10 - 16:35	SEL1L-HRD1 ER-Associated Degradation: From Mechanism to Physiology Ling QI (University of Virginia)
16:35 - 17:00	Structure of ATAD1 Reveals a Linker-enabled Substrate Extraction Mechanism by a Membrane-bound Protein Dislocase Lan WANG (HKUST)
17:00 - 17:15	Regulation of the Host Immune Response to Infection by the Cytoskeleton Network Yaming JIU (Shanghai Institute of Immunity and Infection, Chinese Academy of Sciences)
17:15 - 17:30	Mechano-regulation of Cellular Organelles Congying WU (Peking University)
17:30 - 18:20	Flash Talks and Poster Session
18:30 - 20:30	Dinner (By invitation; Location: Hung Kee Seafood Restaurant)

 

Session V: Capturing Membrane Remodeling Across Time and Space Session Chair: Baiying LI, Hong Kong Baptist University; Co-Chair: Zizhen LIANG, The Chinese University of Hong Kong
09:00 - 09:45	Keynote Lecture: Biogenesis and Function of Plant Vacuole Liwen JIANG (The Chinese University of Hong Kong)
09:45 - 10:10	Lysosomal Roles in Longevity Regulation Meng WANG (Howard Hughes Medical Institute)
10:10 - 10:35	Too Tense to Grow: How Membrane Tension Redirects TORC1 to Trigger Cell Cycle Arrest David BANFIELD (HKUST)
10:35 - 10:50	Coffee Break and Poster Session
10:50 - 11:15	Multiscale Cryo-electron Tomography Reveals Molecular Mechanisms in the Eukaryotic Secretory Pathway Guilia ZANETTI (The Francis Crick Institute)
11:15 - 11:40	Pushing Inward: A New Mechanism of Membrane Invagination Driven by External Force Qiangjun ZHOU (Vanderbilt University)
11:40 - 12:05	Mitochondria Acidify Lysosomes Through Membrane Contact Sites Jiajie DIAO (University of Cincinnati)
12:05 - 12:20	How Cells Make Membrane Proteins Haoxi WU (University of Oxford)
12:20 - 12:35	Multiple Functions of Atg8 in Autophagosome Formation Zhiping XIE (Shanghai Jiao Tong University)
12:35 - 14:00	Lunch Break and Poster Session
Session VI: The Secretory Pathway: Taking the Past to the Future Session Chair: Congyan ZHANG, The Chinese University of Hong Kong; Co-Chair: Ziqing PENG: HKUST
14:00 - 14:45	Keynote Lecture: Extracellular Vesicles and Plasma Membrane Repair Randy SCHEKMAN (University of California, Berkeley; IAS Senior Visiting Fellow)
14:45 - 15:10	Golgi Structure Formation, Function, and Defects in Diseases Yanzhuang WANG (Shenzhen Bay Laboratory)
15:10 - 15:35	Regulation of Microtubule Growth Initiation by Non-Canonical Protein Phosphorylation Robert Zhong QI (HKUST (GZ))
15:35 - 16:00	MBoC Early Career Awardee presentation
16:00 - 16:20	Coffee Break
16:20 - 16:45	Directional Membrane Traffic via Erv14/cornichon Liz MILLER (University of Dundee)
16:45 - 17:10	SURFing and TURFing the Secretory Pathway Xiao-Wei CHEN (Peking University)
17:10 - 17:35	Deciphering Collagen Secretion through Vesicle Proteomics Yusong GUO (HKUST)
17:35 - 18:00	Poster Award / Concluding Remarks
18:30 - 20:30	Dinner (By invitation; Location: Café 103)